Expert Knowledge

Medical focuses

Histopathology
The major task of histopathology is the examination of tissue samples (needle and endoscopic biopsies, surgical biopsies, resection specimen). The aim is a precise diagnosis to serve as a basis for decisions on further diagnostic procedures or therapy.
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Intraoperative diagnostics
During surgery tissue samples can be examined and diagnosis rendered within minutes, either by frozen section technique or imprint cytology. Diagnoses are provided that have an immediate impact an decisions taken during the surgical procedure.
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Cytology
In cytology the analysis of single cells can lead to a diagnosis. These cells can be recovered from bodily fluids (urine) or effusions (ascites, pleura), and from tissue scrapings, or they can be obtained by fine needle aspiration technique. Cytology can serve as a screening method or as a keyhole cancer diagnostic technique. Cytology is therefore important in both cancer prevention as well as diagnosis and staging of manifest disease.
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Diagnostic Molecular Pathology

Molecular pathology is using techniques derived from molecular biology (e.g. PCR, CISH, FISH) as an important adjunct of histological diagnosis. It can provide for subclassification of disease and for prognostication. Infectious agents are rapidly detected and identified. In familial tumors it provides the basis for genetic counselling.
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Diagnostic Tumor Genome Analysis (Next-generation sequencing NGS)
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Immune histochemistry (In situ Techniques)
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Electron microscopy
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Centralized Tissue and Cell Biobank USZ
 
Autopsy
Autopsies are performed for quality assurance and for medical education.
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The Institute of Pathology and Molecular Pathology has an accreditation in accordance with the standard ISO/IEC 17020 and ISO/IEC 17025.