Our services

Laboratories and services

Our services include morphologic (macroscopic, histological, cytological, electron microscopic), histochemical, immune-histochemical, biochemical and molecular-biological examinations of all organs. There are several laboratories for histological and cytological as well as for special investigations. In the department is a patient ambulatory for fine needle puncture. The optinal asservation of the services immediate processing and evaluation ensure highest quality.

Methods in general

  • Histological stainings and special stainings
  • Immune histochemistry, immune fluorescence, enzyme histochemistry
  • Molecular Tumor Profiling, NGS (Next-Generation Sequencing)
  • Molecular biology: In-situ hybridisation, FISH, Southern Blot, PCR
  • Electron microscopy

Histopathology and Intraoperativ Diagnosis

Histopathology and Intraoperativ Diagnosis

Related Information (German)

Diagnostic information
Phone +41 44 255 25 11
pathologie@usz.ch
Laboratory information
Phone +41 44 255 96 45

 

University Hospital Zurich
Institut of Pathology and Molecular Pathology
Histologielabor PATH F 1
Schmelzbergstrasse 12
8091 Zürich

 

Submission of tissue samples (German)

 
Cytology

Cytology

Related Information (German)

walk-in clinic for fine-needle aspiration PATH E 5 (map)
Appointments and information
Phone +41 44 255 39 41
pathologie@usz.ch
Application Form (German, PDF)

 

Contact address
UniversitätsSpital Zürich
Institut für Pathologie und Molekularpathologie
Frau Silvia Aliesch
Leitende Biomed. Analytikerin
Rämistrasse 100
8091 Zürich
silvia.aliesch@usz.ch

 

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology

Related Information (german)

Contact address
Prof. Dieter Zimmermann PhD
Phone +41 44 255 25 22
dieter.zimmermann@usz.ch

locum
Kirsten Struckmann PhD
Phone +41 44 255 16 66
kirsten.struckmann@usz.ch

Ulrike Camenisch PhD
Phone +41 44 255 16 66
Ulrike.CamenischGross@usz.ch

 

University Hospital Zurich
Institute of Pathology and Molecular Pathology
Rämistrasse 100
8091 Zurich

 
Diagnostic Tumor Genome Analysis (Next-Generation Sequencing, NGS)

Diagnostic Tumor Genome Analysis (Next-Generation Sequencing, NGS)

Related Information (german)

Molecular Diagnostics using resections, biopsies, or cytological smears. The analysis includes the detection of mutations using DNA and/or translocations (rearrangements / fusiontranscripts) using RNA. NGS allows the analysis of multiple genes in parallel and is a multiplex-PCR similar to Sanger Sequencing. The detection of translocations by NGS is similar to fluorescence in-situ hybridization (FISH).
The majority of the analyses can be performed using either fixed or fresh material (i.e., FFPE, EDTA-blood, frozen tissue, FNP, unfixed tissue (Direction PDF).

Form for the Diagnostic Tumor Genome Analysis
Order form to fill out and print
General informed consent form for research

Panel description

Mutationanalysis fast-track (Results within 24 - 48h):
Idylla™ NRAS-BRAF Mutations Test (Flyer)
Idylla™ KRAS Mutations Test (Flyer)
Idylla™ EGFR Mutations Test (Flyer)

Systematic search for Drug Targets in solid tumors (mutations, amplifications, gen fusions):
Oncomine Focus Assay™ Panel (DNA, RNA) -> gene list (XLS | PDF)

Liquid Biopsy (Analyses of circulating tumor DNA in plasma):
Oncomine Focus Assay™ Panel (DNA) -> gene list (XLS | PDF)

Therapy stratification of patients with ovarian cancer (all coding exons):
OncomineBRCA Research Assay (Flyer)

Therapy stratification of patients with CLL (all coding exons)
Ion AmpliSeq™ TP53 Panel

Often mutated gens (54) in patients with myeloid diseases (e.g. AML):
TruSight Myeloid® Sequencing Panel (Flyer) -> gene list (XLS | PDF)

Often translocated gens (26) in patients with sarcomas
Archer Sarcoma Panel (Flyer) --> gene list translocation ( XLS | PDF )

Information NGS
ngs.pathologie@usz.ch
Phone +41 44 255 39 29

Dr. rer. nat. Nadejda Valtcheva
nadejda.valtcheva@usz.ch
Dr. rer. nat. Christine Fritz
christine.fritz@usz.ch
Dr. sc. nat. Sandra Freiberger
sandra.freiberger@usz.ch

Contact address laboratory
Dr. sc. nat. Markus Rechsteiner
Phone +41 44 255 39 29
markus.rechsteiner@usz.ch

 

University Hospital Zurich
Institute of Pathology and Molecular Pathology
Rämistrasse 100
8091 Zurich
Switzerland

 
Molecular Tumor Profiling Foundation One

Molecular Tumor Profiling


FoundationOne® provides a comprehensive molecular tumour profile for solid tumors which can support doctors in their decisions regarding the treatment of cancer patients by detecting genetic changes associated with cancer.
more information

Order Form FoundationOne® Service
Order Form | Modulo di richiesta | Formulaire de commandeEinsendeformular

Further Information to the Order
Specimen Instructions

Information 
Molecular Tumor Profiling and FoundationOne® Services
Dr. rer. nat. Martin Zoche
Phone +41 43 253 03 34
Mobile +41 79 788 91 57
martin.zoche@usz.ch

Collaboration Partners
As licensee of the Foundation Medicine® Services outside of the US, Roche has sublicensed the provision of these services in Switzerland to the UniversitätsSpital Zürich.


Hoffmann La Roche AG, Basel, Switzerland
 
Foundation Medicine, Cambridge, USA

Immune histochemistry - In situ Techniques

Immune histochemistry - In situ Techniques Related Information (German)

Information FISH
PATH D 47
Phone +41 44 255 19 87

Information immune histochemistry
André Fitsche
PATH D 53
Phone +41 44 255 14 75
andre.fitsche@usz.ch

Information diagnostics
Prof. Alex Soltermann
PATH C 43
Phone +41 44 255 23 19
alex.soltermann@usz.ch

 

University Hospital Zurich
Institute of Pathology and Molecular Pathology
Rämistrasse 100
8091 Zurich
Switzerland